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在阿尔茨海默氏病的APOE4敲入小鼠模型中的视网膜功能障碍

Surabhi D Abhyankar1,2, Qianyi Luo1, Gabriella D Hartman1,3

  • 1Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, Indiana, USA.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|January 3, 2025
PubMed
概括

APOE4基因变异显著增加晚发性阿尔茨海默病 (LOAD) 的风险,导致视网膜退化. 这项针对APOE4小鼠的研究揭示了与神经炎症相关的视网膜损伤,这表明视网膜是LOAD的潜在生物标志物.

关键词:
在这里,APOEOE是APOE.晚期发作的阿尔茨海默氏病生物标志物生物标志物视网膜 视网膜 视网膜 是一个视网膜功能障碍 视网膜功能障碍

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