高清,视频速率三通道NIR-II成像使用无影灯激发和照明
Yuhuang Zhang1, Shiyi Peng1, Jian Guo2
1State Key Laboratory of Extreme Photonics and Instrumentations, Centre for Optical and Electromagnetic Research, College of Optical Science and Engineering, International Research Center for Advanced Photonics, Zhejiang University, Hangzhou 310058, China.
ACS nano
|January 3, 2025
概括
使用第二个近红外窗口 (NIR-II) 的新多通道成像系统提供了清晰的实时外科导航. 这种视频率系统简化了光源,提高了安全性,减少了交叉通话,以改善外科视觉.
科学领域:
- 生物医学光学 生物医学光学
- 医疗成像医学成像
- 手术导航 手术导航
背景情况:
- 在第二个近红外 (NIR-II) 窗口中的多通道成像对于复杂的外科环境至关重要.
- 现有的方法往往缺乏简单性,高质量,视频速率能力,或有安全问题.
- 需要一个安全,高效,高性能的多通道成像解决方案,用于手术.
研究的目的:
- 开发一种用于外科导航的简单,高质量的视频速率多通道成像方法.
- 为了减少与外科成像中的激发光源相关的安全风险.
- 为了实现实时,高性能成像,在NIR-II窗口中最小的交叉声.
主要方法:
- 开发了一种使用NIR-IIx窗口 (1400-1500 nm) 和NIR-IIc窗口 (1000-1100 nm和1700-1880 nm) 的三通道成像系统.
- 实现了多通道成像辅助的外科导航模式.
- 采用标准的无阴影灯激发和照明,不需要额外的激发光源.
主要成果:
- 在指定NIR-II频段的三通道成像中实现了特殊的清晰度.
- 显示了令人印象深刻的信号与交叉通话比率高达22.10.
- 在环境照明下以每秒25 (fps) 的视频率运行系统.
结论:
- 开发的系统提供了一个实用的光手术导航范式.
- 提供实时,高成像性能多通道成像与最小交叉通话的参考.
- 简化光源并降低安全风险,以增强手术可视化.
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