影响人类牙的年龄相关变化的纳米结构分析
Chika Akabane1, Mitsuo Kimura2, Yukio Yamamoto2
1Research and Development Headquarters, LION Corporation, 7 Chome-2-1, Hirai, Edogawa, Tokyo, 132-0035, Japan. chika_a@lion.co.jp.
Calcified tissue international
|January 3, 2025
概括
人类牙是人类的牙.
科学领域:
- 生物材料科学 生物材料科学
- 纳米技术纳米技术
- 牙科研究 牙科研究
背景情况:
- 人类牙的终身功能需要极端的耐用性,以抵御重复的负荷.
- 了解牙的纳米结构和与年龄相关的变化对于阐明其机械性质至关重要.
- 之前的研究对牙的整体纳米结构和衰老效应进行了有限的综合分析.
研究的目的:
- 为了描述人类牙的矿物颗粒特征.
- 用先进的X射线散射技术研究牙纳米结构的与年龄相关的变化.
主要方法:
- 使用同步扫描小和广角X射线散射 (SAXS/WAXS).
- 分析了30个人类牙和前牙,来自16岁至77岁的个体.
- 获取纳米结构特征的2D地图,以评估矿物颗粒的大小,方向和厚度.
主要成果:
- 鉴定了矿物颗粒大小向纤维细胞室的负梯度.
- 观察到矿物颗粒的位置依赖的偏好方向,在牙类型中一致.
- 在内冠中发现与年龄相关的矿物颗粒厚度显著增加.
结论:
- 丹丁的纳米结构表现出明显的梯度和方向模式.
- 与年龄相关的变化,特别是矿物颗粒厚度的增加,可能会导致管管封闭.
- 这些纳米结构的改变可能会影响牙的机械性能和耐用性.
更多相关视频
08:12Micro-dissection of Enamel Organ from Mandibular Incisor of Rats Exposed to Environmental Toxicants
Published on: March 29, 2018
10.0K
07:10A Sectioning, Coring, and Image Processing Guide for High-Throughput Cortical Bone Sample Procurement and Analysis for Synchrotron Micro-CT
Published on: June 12, 2020
5.0K
相关概念视频
01:29Bone Disorders
3.3K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
3.3K
01:15Teeth
237
The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
237