乳头节省乳房切除术中的古老问题:年龄较大是否是一种禁忌?
Francys C Verdial1, Kyle J Anderman2, Abigail E Daly2
1Breast Surgery Section, Division of GI and Oncologic Surgery, Massachusetts General Hospital, Boston, MA, USA. fverdial@mgh.harvard.edu.
Annals of surgical oncology
|January 3, 2025
概括
老年妇女可以安全地接受乳头节省乳房切除术 (NSM) 与植入物重建,因为晚年不是并发症的预测因素. 患者因素,而不是年龄,影响结果,引导更好的患者选择NSM.
科学领域:
- 在瘤学瘤学.
- 整形外科 整形外科 整形外科
- 老年医学 老年医学
背景情况:
- 乳头节约性乳房切除术 (NSM) 在老年妇女中未得到充分利用,因为人们担心与年龄有关的并发症.
- 这项研究评估了老年人群中NSM的术后结果和风险因素.
研究的目的:
- 评估NSM的安全性和并发症率与老年妇女的立即植入物基础的重建.
- 在这个人口群体中识别并发症和重建失败的风险因素.
主要方法:
- 对1998年立即植入器重建的NSM进行回顾性审查 (2009-2019).
- 跨年龄组结果的比较:45-54岁,55-64岁和≥65岁.
- 多变量回归分析以确定并发症和重建失败的独立风险因素.
主要成果:
- 65岁或以上的妇女患病并发症和早期术后并发症的比率较高,特别是血液瘤.
- 单变量分析显示,感染,亡,严重并发症或因年龄而导致的重建失败没有显著差异.
- 多变量分析显示,年龄不是一个独立的预测因素;吸烟,糖尿病,高血压,抗凝血剂和之前的放射治疗是显著的风险因素.
结论:
- 高龄不是乳头节省乳房切除术后并发症或重建失败的独立风险因素.
- 患者特定的因素,如吸烟和并发症,在预测结果方面更为关键.
- 对功能和生活质量结果的进一步研究可以改进老年女性对NSM的患者选择.
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