,catecholaminergic姿

John G Pagiazitis1, Nicolas Delestrée2, Leonie Sowoidnich3

  • 1Center for Motor Neuron Biology and Disease, Columbia University, New York, NY 10032, USA; Department of Neurology, Columbia University, New York, NY 10032, USA; Department of Physiology, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki 541 24, Greece.

Cell reports
|January 3, 2025
PubMed
概括

脊椎肌肉缩 (SMA) 由于失去了儿科质突触,导致运动缺陷. 在特定的神经元中恢复生存运动神经元 (SMN) 改善了运动,但需要联合治疗或l-dopa来纠正姿势.