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Updated: Jul 9, 2026

Nuclei Isolation from Fresh Frozen Brain Tumors for Single-Nucleus RNA-seq and ATAC-seq
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在人类质母细胞瘤中,子心室区域的单核和空间景观

Yamhilette Licón-Muñoz1, Vanessa Avalos1, Suganya Subramanian2

  • 1The Brain Tumor Translational Laboratory, Department of Cell Biology and Physiology, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA; University of New Mexico Comprehensive Cancer Center, Albuquerque, NM 87131, USA.

Cell reports
|January 3, 2025
PubMed
概括

质母细胞瘤 (GBM) 癌症干细胞位于大脑的腹腔下区域 (SVZ),驱动治疗阻力. 这项研究揭示了支持瘤的微质,并确定了IL-1β和Wnt-5a通路作为SVZ微环境中的潜在治疗标.

关键词:
CP: 癌症 癌症 癌症大脑瘤 大脑瘤癌症类似干细胞的细胞.质母细胞瘤 (glioblastoma) 是一种副腹腔区域 副腹腔区域瘤微环境是一个微环境.

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