基于SOFA评分,预测患有未破裂腹腔大动脉动脉瘤的患者需要手术的情况
Chao Weng1, Cong Yu1, Guang-Wei Yang1
1General Surgery, Cancer Center, Department of Vascular Surgery, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, China.
PloS one
|January 3, 2025
概括
序列器官衰竭评估 (SOFA) 评分是患有未破裂腹腔大动脉瘤 (AAA) 患者需要手术的有价值预测指标. 较高的SOFA分数与增加的不良事件相关,包括死亡率.
科学领域:
- 心血管外科心血管外科
- 关键护理医学 关键护理医学
- 医疗信息学 医疗信息学
背景情况:
- 未破裂的腹腔大动脉动脉瘤 (AAA) 具有重大风险,需要准确预测不良事件.
- 序列器官衰竭评估 (SOFA) 评分在预测AAA患者的结果中的临床实用性仍未得到充分研究.
研究的目的:
- 调查SOFA得分与未破裂AAA患者的不良事件之间的关联.
- 评估SOFA得分在预测需要手术 (NFS) 和其他不良结果方面的临床价值.
主要方法:
- 从密集护理IV数据库中对322名患者进行了回顾性分析.
- 后勤回归,ROC分析和名图构造,以评估SOFA对NFS的预测性能.
- 使用回归模型和决策曲线分析,探索SOFA与住院时间 (LOS),ICU-LOS和住院死亡率的关联.
主要成果:
- 在原始模型和调整模型中,高的SOFA分数与NFS显著相关 (P<0.05).
- SOFA显示了NFS的有利预测性能 (AUC = 0.701),与乳酸和性别相结合时会有所改善 (AUC = 0.888).
- SOFA还显示了与医院LOS,ICU-LOS和住院死亡率的显著相关性,具有7天医院LOS和住院死亡率的预测价值.
结论:
- SOFA评分与未破裂AAA.患者手术的需要有显著关系.
- 在这种患者群体中,SOFA 作为预测需要手术和其他不良结果的有用指标.
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