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Updated: May 7, 2025

Analysis of LINE-1 Retrotransposition at the Single Nucleus Level
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Analysis of LINE-1 Retrotransposition at the Single Nucleus Level

Published on: April 23, 2016

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端粒逆转移子与细胞周期的转录合

Mengmeng Liu1, Xiao-Jun Xie2, Xiao Li2

  • 1Department of Biochemistry and Molecular Biology, Tulane University School of Medicine, Louisiana Cancer Research Center, 1700 Tulane Avenue, New Orleans, LA 70112, USA.

Science advances
|January 3, 2025
PubMed
概括

在Drosophila中,调解者复合体和Sd/dTEAD通过E2F1-Dp调节端粒逆转移素 (TR) 转录. 这种机制将细胞循环机制与端粒维护联系起来,保护染色体末端.

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As the name suggests, non-LTR retrotransposons lack the long terminal repeats characteristic of the LTR retrotransposons. Additionally, both LTR and non-LTR retrotransposons use distinct mechanisms of mobilization. Non-LTR retrotransposons are further divided into two classes - Long interspersed nuclear elements (LINEs) and short interspersed nuclear elements (SINEs), both of which occur abundantly in most mammals, including humans. Some of the active non-LTR retrotransposons in humans are L1...
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