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Updated: Jun 4, 2025

Simultaneous Mapping and Quantitation of Ribonucleotides in Human Mitochondrial DNA
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内核酶G通过选择性增加线粒体tRNAThr生产来促进肝脏线粒体呼吸

Xihui Xu1, Rozhin Penjweini2, Lóránt Székvölgyi3

  • 1Laboratory of Obesity and Aging Research, Cardiovascular Branch, National Heart Lung and Blood Institute, NIH, Bethesda, MD 20892.

Proceedings of the National Academy of Sciences of the United States of America
|January 3, 2025
PubMed
概括

线粒体内核酶G (EndoG) 对于男性肝脏健康至关重要,通过调节线粒体tRNA生产来促进呼吸. EndoG 缺乏会损害这一过程,导致男性的代谢功能障碍相关的脂肪性肝病 (MASLD).

关键词:
马斯尔德 马斯尔德是什么意思内核酶G的内核酶是什么线粒体中的线粒体.这是一个tRNARNA.

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