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线粒体DNA谱系通过T细胞反应性氧气信号来决定瘤的进展

Tal Yardeni1,2, Arnold Z Olali1, Hsiao-Wen Chen1

  • 1Center for Mitochondrial and Epigenomic Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA 19104.

Proceedings of the National Academy of Sciences of the United States of America
|January 3, 2025
PubMed
概括

主体线粒体DNA (mtDNA) 影响免疫细胞功能和癌症进展. 特定的mtDNA谱系会损害T调节细胞功能,阻碍抗瘤免疫力和全移植存活.

关键词:
收养转移 收养转移癌症 癌症 癌症 癌症 癌症免疫疗法 免疫疗法线粒体DNA是线粒体DNA的组成部分.有活性氧物种的反应性氧物种.

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