双相情感障碍的父母是否有更高的患有多动症的后代的风险? 一个系统的审查
Leandro L Ferreira1, Antonio E Nardi1, Laiana A Quagliato1
1Institute of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Trends in psychiatry and psychotherapy
|January 3, 2025
概括
父母被诊断患有双相情感障碍 (BD) 的儿童,患有注意力缺陷多动症障碍 (ADHD) 的风险增加. 需要进一步的研究来了解这些疾病之间的生物联系.
科学领域:
- 精神病学是一个精神病学.
- 遗传学 遗传学 是一个
- 儿科 儿科 儿科
背景情况:
- 双相情感障碍 (BD) 和注意力缺陷多动症障碍 (ADHD) 的父母的后代有这些疾病的风险增加.
- 在BD和ADHD之间存在共享的精神病理症状,但它们的遗传重叠尚未得到充分理解.
研究的目的:
- 系统地审查和评估父母患有双相情感障碍 (BD) 的后代注意力缺陷多动症 (ADHD) 的风险.
主要方法:
- 通过使用PubMed,SciELO,PsycInfo和Cochrane数据库进行了系统审查,直到2024年8月12日.
- 包括专注于父母BD和后代结果的研究,使用验证的诊断标准 (DSM/ICD).
- 偏差风险使用纽卡斯尔-太华尺度进行评估.
主要成果:
- 二十三篇文章符合列入标准.
- 大多数研究表明,父母患有BD的后代患有ADHD的风险更高.
- 与对照组相比,病例控制研究始终显示病例组的ADHD风险较高.
结论:
- 关于父母BD和后代ADHD之间的关联现有的研究是异质的.
- 生物相关性,包括遗传,生物化学,神经成像和神经心理学方面,需要进一步调查.
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