相关实验视频

Updated: Jun 4, 2025

Combined Invasive Subcortical and Non-invasive Surface Neurophysiological Recordings for the Assessment of Cognitive and Emotional Functions in Humans

Combined Invasive Subcortical and Non-invasive Surface Neurophysiological Recordings for the Assessment of Cognitive and Emotional Functions in Humans

Published on: May 19, 2016

对深度大脑刺激的成本效益分析与对抗治疗耐药强迫症障碍的常规治疗相比

Ricardo A Najera¹, Katherine E Kabotyanski¹, Nicole C McLaughlin²

¹1Department of Neurosurgery, Baylor College of Medicine, Houston, Texas.

Journal of neurosurgery

|January 3, 2025

概括

可充电深度大脑刺激 (DBS) 是治疗耐药强迫症 (OCD) 的成本效益高. 非充电式DBS可能会变得具有成本效益,因为电池寿命有所改善,支付意愿值有所调整.

科学领域:

神经外科神经外科
卫生经济学卫生经济学
精神病学是一个精神病学.

背景情况:

深度大脑刺激 (DBS) 是对耐药强迫症 (OCD) 的有效治疗方法.
与运动障碍相比,对于精神疾病的DBS的经济分析有限.
DBS提供了可逆性和可调性,与神经衰竭手术相比具有优势.

研究的目的:

在美国进行第一个针对治疗耐药性强迫症的DBS的成本效益分析.
为了比较DBS与通常治疗 (TAU) 的成本效益.
评估不同的DBS设备类型 (可充电与非可充电) 和时间范围 (3年与5年).

主要方法:

开发了四个决策分析模型,将DBS与TAU进行比较.
从文献评论中结合治疗反应和并发症率.
利用蒙特卡洛模拟和概率灵敏度分析来估计ICERs (每QALY的美元).

主要成果:

可充电DBS模型在不同的支付意愿 (WTP) 门中,与TAU相比,证明了成本效益.
在传统的美国WTP门下,非可充电DBS模型的成本效益较低,但在世卫组织公约下显示出潜在的成本效益.
概率灵敏度分析表明可充电DBS的成本效益很高,特别是在更高的WTP值时.

结论:

可充电的DBS是治疗耐药性强迫症患者的经济有效选择.
随着技术的进步和不断变化的经济标准,不可充电的DBS可能会变得更具成本效益.
这些发现支持DBS作为耐火性强迫症治疗的经济可行性.

关键词:

在 DBS 中,DBS 是 DBS 的代名词.这是OCD的OCD.深度大脑刺激刺激大脑功能神经外科功能神经外科卫生经济学卫生经济学卫生公平性健康公平性通过神经调节进行神经调节.强迫症是一种强迫症.

更多相关视频

Analysis of Gene Expression Changes in the Rat Hippocampus After Deep Brain Stimulation of the Anterior Thalamic Nucleus

Analysis of Gene Expression Changes in the Rat Hippocampus After Deep Brain Stimulation of the Anterior Thalamic Nucleus

Published on: March 8, 2015

MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder

MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder

Published on: August 11, 2015

相关概念视频

Electroconvulsive Therapy

Electroconvulsive Therapy

Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early...

Psychosurgery

Psychosurgery

Psychosurgery, the surgical alteration or permanent removal of brain tissue to alleviate severe psychological conditions, stands as one of the most radical and controversial treatments in the history of mental health care. Its development and application have evolved significantly, marked by dramatic shifts in scientific understanding and ethical perspectives.
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...

Obsessive-Compulsive Disorder

Obsessive-Compulsive Disorder

Obsessive-compulsive disorder (OCD) is a mental health condition characterized by recurrent obsessions, compulsions, or both, which consume significant time and interfere with daily functioning. Obsessions involve persistent, intrusive, and unwanted thoughts, images, or urges that evoke anxiety. Common examples include irrational fears of contamination or harm. Compulsions are repetitive behaviors or mental acts performed to reduce the anxiety caused by obsessions. For instance, individuals...

Operant Conditioning Intervention

Operant Conditioning Intervention

Operant conditioning serves as a foundational principle in therapeutic interventions aimed at modifying maladaptive behaviors. Central to this approach is the notion that behaviors, both adaptive and maladaptive, are learned through reinforcement. By analyzing the environmental factors that reinforce problematic behaviors, clinicians can design interventions to weaken these reinforcements and replace maladaptive behaviors with healthier alternatives.
In operant conditioning, behaviors that are...