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新型抗疟疾药物3-替代诺异体,具有改善的药理动力学特性

Siyuan Ge1, Rongchao Jian2, Qiwei Xuan3

  • 1School of Pharmacy and Food Engineering, Wuyi University, 529020, Jiangmen, China; Department of Chemistry, University of Liverpool, L69 7ZD, Liverpool, UK; Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong Special Administrative Region of China.

European journal of medicinal chemistry
|January 3, 2025
PubMed
概括

新型抗疟疾化合物具有更好的溶解性,通过用生物异构剂取代诺核心来开发. 这一策略增强了更好的疟疾治疗药物特性,在早期研究中显示出有前途的结果.

关键词:
这是一种抗疟疾药.生物异构体 生物异构体原菌 (Plasmodium falciparum) 是一种有毒的病毒.昆诺隆 (quinolone) 是一种氨酸.可溶性 可溶性 溶性

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