对具有潜伏嵌入多变量回归的多条件单细胞数据的分析

Constantin Ahlmann-Eltze1,2, Wolfgang Huber3

  • 1Genome Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany. constantin.ahlmann@embl.de.

Nature genetics
|January 3, 2025
PubMed
概括

这项研究引入了潜伏嵌入多变量回归 (LEMUR),这是一种用于分析单细胞RNA测序数据中的基因表达的新方法. 没有离散的细胞类型集群的LEMUR模型持续生物变异,提供更广泛的适用性.

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