功能与心脏代谢风险因素,人体指数和伊朗普通人口的饮食炎症指数之间的关系:一个横截面研究
Samaneh Madani1, Seyed Jalil Masoumi2,3,4, Afsane Ahmadi5
1School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.
BMC nephrology
|January 3, 2025
概括
慢性病 (CKD) 与心脏代谢因素有关. 年龄,性别,脂质概况,血压和体重显著影响功能,突出了潜在的干预领域.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 心脏病学 心脏病学
- 代谢健康 代谢健康
背景情况:
- 慢性病 (CKD) 影响全球13.4%的患者,并导致大量的医疗保健费用.
- 慢性病的危险因素包括遗传倾向,代谢障碍和生活方式选择.
- 了解CKD的多因素性质对于公共卫生战略至关重要.
研究的目的:
- 调查功能和心脏代谢风险因素之间的关联.
- 探索人类特征与功能之间的关系.
- 确定饮食炎症指数 (DII) 在伊朗人口脏健康中的作用.
主要方法:
- 在希拉兹医学科学大学对2472名员工进行横截面研究.
- 通过血清肌素 (sCr),血液尿素 (BUN) 和估计的淋巴细胞过率 (eGFR) 评估功能.
- 生物化学标记,血压,人体指数和饮食摄入量 (DII) 的综合评估.
- 多变量线性回归用于识别影响功能的因素.
主要成果:
- 观察到sCr和空腹血糖 (FBS),甘油三 (TG),高血糖,腹血压 (DBP),体重 (Wt) 和身体脂肪指数 (BAI) 之间存在显著的直接关系.
- BUN显示与年龄,TG,HDL和BAI有直接关系.
- eGFR与缩血压 (SBP),Wt,BAI和内脏脂肪指数 (VAI) 呈反向关系.
- 与男性相比,女性的sCr和BUN水平较低,eGFR水平较高.
结论:
- 年龄,性别,脂质概况,血糖状况,血压 (BP),BAI,VAI和Wt与功能有关.
- 这些因素代表了管理和潜在地预防CKD的关键目标.
- 进一步的研究可以阐明将这些因素与脏健康联系在一起的具体机制.
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