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超越CTLA-4和PD-1:对MAO-A作为癌症免疫疗法下一代免疫检查点调节器的新见解

Prajna Maity1, Debjeet Sur1

  • 1Division of Pharmacology, Guru Nanak Institute of Pharmaceutical Science and Technology, Kolkata, 700114, India.

Current cancer drug targets
|January 4, 2025
PubMed
概括

单胺氧化酶A (MAO-A) 抑制重新编程与瘤相关的巨细胞,增强CD8+ T细胞活性,用于潜在的癌症免疫疗法. 向MAO-A可能比目前的免疫检查点阻塞疗法提供更安全,更有效的治疗方法.

关键词:
CD8+ T 细胞 CD8+ T 细胞单胺氧化酶 (MAO) 是一种单胺氧化酶.癌症 癌症 癌症 癌症 癌症免疫检查点是一个检查点.免疫检查点调节器这是一种血清素. 血清素.

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