比较功能性体力综合征,压力相关综合征和健康对照患者的自主神经系统功能
Maaike Van Den Houte1, Indra Ramakers2, Lukas Van Oudenhove3
1REVAL - Rehabilitation Research Center, Faculty of Rehabilitation Sciences, Hasselt University, Diepenbeek, Belgium; Laboratory for Brain-Gut Axis Studies (LaBGAS), Translational Research Center for Gastrointestinal Disorders (TARGID), Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium; Leuven Brain Institute, KU Leuven, Leuven, Belgium.
Journal of psychosomatic research
|January 4, 2025
概括
患有功能性体力综合征和与压力相关的综合征的患者表现出交感神经系统的主导地位,这表明在这些条件下自主功能障碍是常见的. 这会影响压力和恢复期间的心率和心率的变化.
科学领域:
- 神经科学是一个神经科学.
- 心理生理学 心理生理学
- 临床医学 临床医学
背景情况:
- 功能性体征综合征 (FSS) 和与压力相关的综合征 (SRS) 是复杂的疾病,通常与自主神经系统 (ANS) 功能障碍有关.
- 了解ANS对压力的反应对于诊断和管理这些综合征至关重要.
研究的目的:
- 与健康对照组 (HC) 相比,研究FSS和SRS患者的ANS功能.
- 在心理社会压力和恢复期间测量心率 (HR),心率变化 (HRV),皮肤导电水平 (SCL) 和皮肤温度 (ST).
主要方法:
- 一组26名FSS患者,59名SRS患者和30名HC患者接受了标准化心理社会压力测试.
- 在休息,压力和恢复阶段持续监测HR,HRV,SCL和ST.
主要成果:
- 与休息时的HC相比,患有FSS和SRS的患者表现出更高的平均HR和SCL,以及更低的HRV.
- 与HC相比,这两组患者在压力期间都显示出平淡的HR增加,并在康复期间显示出较小的HR减少.
- 患有FSS的患者表现出比HC更大的SC应激反应,并且HRV在康复期间在两组患者中都较低.
结论:
- 自主神经系统功能障碍,以同情神经系统主导为特征,是FSS和SRS的跨诊断特征.
- 这些发现凸显了ANS失调在这些综合征的病理生理学中的重要作用.
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