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Updated: Jul 4, 2026

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提升VAPB-PTPIP51的整合修复了受损的线粒体相关的内质网膜,并抑制了肺纤维细胞激活

Jiaqi Ban1, Hongru Tian1, Yungeng Wei2

  • 1School of Public Health, the key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, Guiyang, Guizhou, 561113, China.

International immunopharmacology
|January 4, 2025
PubMed
概括

粉通过激活纤维细胞引起肺纤维化. 这项研究表明,线粒体关联的细胞内网膜 (MAM) 在这个过程中至关重要,干预可以修复MAM以减轻肺损伤.

关键词:
细胞内膜网膜应激压力肺部纤维细胞是如何形成的线粒体关联的内细胞网膜膜.线粒体损伤导致线粒体损伤.这就是VAPB-PTPIP51的原因.

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