在社区减少危害环境中管理涉及西拉的过量服用:墨西哥蒂华纳的经验教训
Lilia Pacheco Bufanda1,2, Alejando González Montoya3, Brenda Torres Carrillo3
1Prevencasa A.C. Harm Reduction Clinic, Tijuana, Baja California, Mexico. liliapacheco@prevencasa.org.
Harm reduction journal
|January 4, 2025
概括
社区过量剂量应对小组可以通过优先考虑氧化而不是意识来管理涉及西拉的过量剂量. 这种方法对于在纳洛给药后经历长时间镇静的患者至关重要,特别是在联合使用西拉和芬太尼时.
科学领域:
- 紧急医疗 紧急医疗
- 毒理学 毒理学 毒理学
- 公共卫生 公共卫生
背景情况:
- 一种兽医镇静剂西拉 (Xylazine) 越来越多地涉及过量死亡.
- 需要进一步研究的临床管理策略,特别是在社区减少危害的设置中,对于涉及西拉的过量服用,需要进一步研究.
- 本系列详细介绍了在墨西哥蒂华纳 (Tijuana) 发现西拉的经验,以及其新兴的存在.
研究的目的:
- 描述临床方法和社区过量反应小组的经验教训,以管理涉及西拉的过量服用.
- 突出涉及西拉过量剂的独特临床特征,例如长时间的纳洛后镇静.
- 在新遇到xylazine的地区,为减少危害的策略提供信息.
主要方法:
- 介绍了三起临床案例,这些病例涉及在社区减少危害的环境中管理的西拉过量用药.
- 详细描述患者表现,干预措施 (包括纳洛和氧气的使用) 和结果.
- 使用尿液和药物测试来确认西拉和芬太尼的存在.
主要成果:
- 克西拉涉及的过量服用可能会导致长时间的镇静,即使在纳洛给药后.
- 氧化和呼吸道管理对于稳定患者至关重要,意识恢复时间各不相同.
- 在过量服用的情况下,证实了西拉和芬太尼的同时出现.
结论:
- 管理过量用西拉的临床团队应该优先考虑氧化和气道管理,而不是立即意识评估.
- 便携式氧气和现场安全是现场管理的重要组成部分.
- 克西拉检测条可以帮助患者教育有关与物质使用相关的健康风险.
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