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Updated: Jun 4, 2025

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由PSMA4过度表达引起的代谢重编程有助于在多发性骨髓瘤中促进博特佐米布耐药性

Han Yu1, Chengli Wu1, Jie He2

  • 1Department of Oncology, Navy No.905 Hospital of PLA, Naval Medical University, Shanghai, 200052, China.

Annals of hematology
|January 4, 2025
PubMed
概括

多发性髓瘤仍然是无法治愈的. 过度表达PSMA4基因通过增加氧化酸化和激活HIF-1α信号来驱动化学抵抗,从而提供了一个潜在的治疗标.

关键词:
博尔特佐米布的耐药性代谢重编程是一种代谢重编程.骨髓瘤是多发性骨髓瘤的一个组成部分.在WGCNA中,WGCNA是WGCNA.

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