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m6A修饰的pre-miR-503-5p通过mTOR通路的激活,有助于肌原分化

Yalong Su1, Kaiping Deng1, Zhipeng Liu1

  • 1Sanya Research Institute of Nanjing Agricultural University, Nanjing Agricultural University, Sanya 572025, China; Jiangsu Livestock Embryo Engineering Laboratory, College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.

International journal of biological macromolecules
|January 5, 2025
PubMed
概括

以ythdf2为媒介的m6A修饰通过增强miR-503-5p成熟来促进骨肌肉的发育. 这一过程激活了mTOR通路,加速了山羊初级肌细胞中的分化和线粒体生物发生.

关键词:
微RNA的成熟过程肌肉发育 (Myogenesis) 是一种肌肉发育的过程.m6A 修改的修改在 mTOR 路径上.在 miR-503-5p 中使用.

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