Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Gene Therapy00:59

Gene Therapy

24.9K
Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be...
24.9K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Family-Based Preventive Interventions for Problematic Internet Use Among Children and Adolescents: Protocol for a Systematic Review and Meta-Analysis.

International journal of environmental research and public health·2026
Same author

Low-Cost Community-Based Personal Alarm Intervention for Preventing Sexual Victimization in Indian Urban Slums: A Cluster Randomized Controlled Trial.

Journal of interpersonal violence·2026
Same author

The DOCK3-HAUS7 axis: A new paradigm in optic nerve regeneration.

Neural regeneration research·2026
Same author

Correlations between amyloid-β peptide levels in aqueous humor and retinal thickness in patients with glaucoma.

Scientific reports·2025
Same author

Short-term services and risk factors associated with psychological abuse recurrence in Japanese child guidance centers.

Child abuse & neglect·2025
Same author

Role of HAUS7 as a DOCK3 binding partner in facilitating axon regeneration.

Science advances·2025
Same journal

Nihon yakurigaku zasshi. Folia pharmacologica Japonica·2026
Same journal

[Prediction of severe oral mucositis in cancer treatment: the role of the oral-gut axis in precision supportive care].

Nihon yakurigaku zasshi. Folia pharmacologica Japonica·2026
Same journal

[Iron dysregulation and ferroptosis in heart failure: the dual faces of deficiency and overload].

Nihon yakurigaku zasshi. Folia pharmacologica Japonica·2026
Same journal

[Pharmacological characteristics and clinical outcomes of Rimegepant (Nurtec<sup>®</sup> ODT), an oral CGRP receptor antagonist for the acute treatment and prevention of migraine].

Nihon yakurigaku zasshi. Folia pharmacologica Japonica·2026
Same journal

[Pharmacological properties and clinical trial results of datopotamab deruxtecan (Dato-DXd, Datroway<sup>®</sup>)].

Nihon yakurigaku zasshi. Folia pharmacologica Japonica·2026
Same journal

[Oxytocin regulates social familiarity-dependent mate choice in medaka].

Nihon yakurigaku zasshi. Folia pharmacologica Japonica·2026
查看所有相关文章

相关实验视频

Updated: May 7, 2025

Methodology for Biomimetic Chemical Neuromodulation of Rat Retinas with the Neurotransmitter Glutamate In Vitro
12:56

Methodology for Biomimetic Chemical Neuromodulation of Rat Retinas with the Neurotransmitter Glutamate In Vitro

Published on: December 19, 2017

7.7K

[用于恢复视觉功能的基因疗法]

Kazuhiko Namekata1, Xiaoli Guo1, Chikako Harada1

  • 1Visual Research Project, Tokyo Metropolitan Institute of Medical Science.

Nihon yakurigaku zasshi. Folia pharmacologica Japonica
|January 5, 2025
PubMed
概括
此摘要是机器生成的。

基因疗法提供了一种新的方法来治疗眼,这是导致失明的主要原因. 这项研究探讨了使用基因疗法与神经变因子来保护视神经,并可能恢复视力在绿眼病患者.

更多相关视频

Limbal Approach-Subretinal Injection of Viral Vectors for Gene Therapy in Mice Retinal Pigment Epithelium
06:48

Limbal Approach-Subretinal Injection of Viral Vectors for Gene Therapy in Mice Retinal Pigment Epithelium

Published on: August 7, 2015

21.0K
Subretinal Injection of Gene Therapy Vectors and Stem Cells in the Perinatal Mouse Eye
05:09

Subretinal Injection of Gene Therapy Vectors and Stem Cells in the Perinatal Mouse Eye

Published on: November 25, 2012

33.0K

相关实验视频

Last Updated: May 7, 2025

Methodology for Biomimetic Chemical Neuromodulation of Rat Retinas with the Neurotransmitter Glutamate In Vitro
12:56

Methodology for Biomimetic Chemical Neuromodulation of Rat Retinas with the Neurotransmitter Glutamate In Vitro

Published on: December 19, 2017

7.7K
Limbal Approach-Subretinal Injection of Viral Vectors for Gene Therapy in Mice Retinal Pigment Epithelium
06:48

Limbal Approach-Subretinal Injection of Viral Vectors for Gene Therapy in Mice Retinal Pigment Epithelium

Published on: August 7, 2015

21.0K
Subretinal Injection of Gene Therapy Vectors and Stem Cells in the Perinatal Mouse Eye
05:09

Subretinal Injection of Gene Therapy Vectors and Stem Cells in the Perinatal Mouse Eye

Published on: November 25, 2012

33.0K

科学领域:

  • 眼科医生 眼科 眼科
  • 神经科学是一个神经科学.
  • 遗传学 遗传学 是一个

背景情况:

  • 玻璃眼是导致与年龄相关的失明的主要原因,其特点是视神经的神经退行.
  • 目前的治疗方法侧重于降低眼内压力,但对许多患者来说不足,需要新的治疗策略.
  • 基因疗法是一个新兴领域,临床应用越来越多,包括神经退行性疾病.

研究的目的:

  • 为了研究基因疗法的潜力,对玻璃眼治疗.
  • 开发一种新的基因治疗方法,利用神经营养因子信号传递.
  • 为了实现神经保护和轴突再生,在绿眼中恢复视力.

主要方法:

  • 开发和应用基因疗法载体.
  • 使用神经变因子信号通路.
  • 研究神经保护和轴突再生的治疗作用.

主要成果:

  • 这项研究正在研究一种新的基因治疗方法来治疗眼.
  • 研究重点是治疗干预的神经营养因子信号传递.
  • 目的是证明神经保护和促进轴突再生.

结论:

  • 基因疗法作为对玻璃眼的基本治疗方法具有前景.
  • 准神经变因子信号传递可以提供神经保护和视力恢复的双重好处.
  • 需要进一步的开发,以建立基因疗法用于临床绿眼治疗.