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经常吸烟者与从未吸烟者的非小细胞肺癌

Jeremy R Burt^1,2, Naim Qaqish³, Greg Stoddard⁴

¹Department of Radiology, Cardiothoracic Imaging, University of Utah, Spencer Fox Eccles School of Medicine, 50 N Medical Dr, Salt Lake City, UT, 84132, USA. radhopkins@hsc.utah.edu.

|January 5, 2025

概括

患有非小细胞肺癌 (NSCLC) 的非吸烟者 (NS) 与常吸烟者 (S) 的早期生存率相似. 然而,常吸烟者在5年和10年内死亡风险几乎翻了一番.

科学领域:

在瘤学瘤学.
肺部病理学肺部病理学
流行病学流行病学

背景情况:

肺癌是癌症死亡的主要原因之一.
非小细胞肺癌 (NSCLC) 的发病率在从未吸烟者中正在上升.
这项研究比较了从未吸烟者 (NS) 和经常吸烟者 (S) 的NSCLC.

研究的目的:

为了比较NS和SNSCLC患者之间的临床,成像,病理和结果.
根据吸烟史识别NSCLC呈现和预后的显著差异.

主要方法:

对155名NSCLC患者 (67名NS,88名S) 的回顾性队列研究.
在初始活检时评估了临床,成像和病理学发现,以进行分期.
主要结局:全因死亡率;次要结局:12个月无进展生存期.

主要成果:

图像特征 (结节大小,化,入侵) 在NS和S之间是相似的.
更多的NS患者出现胸外转移和第四阶段疾病.
与S患者相比,NS患者更常见的是腺癌组织学,而S患者则更常见.

结论:

在未吸烟者 (NS) 和患有NSCLC的常吸烟者 (S) 中,CT结节的特征相似.
NS患者更常被诊断为转移性腺病和第四阶段疾病.
常吸烟者 (S) 在诊断后5年和10年面临近两倍的死亡风险,尽管早期的生存率相似.

关键词:

所有原因的死亡率.癌症的分期癌症的分期胸部CT CT 的情况.组织病理学组织病理学非小细胞肺癌是非小细胞肺癌.

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