怀孕前孕产妇压力和怀孕年龄小之间的关联:基于人口的回顾性队列研究
Manman Chen1,2, Qiongjie Zhou3, Yuanyuan Li4
1School of Population Medicine and Public Health, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
BMC medicine
|January 5, 2025
概括
怀孕前母亲的压力增加了新生儿怀孕年龄小的风险 (SGA). 较低的社会经济地位加剧了这种风险,特别是生活和经济压力因素.
科学领域:
- 生殖健康 生殖健康
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 公共卫生 公共卫生
背景情况:
- 母亲的压力是影响胎儿发育的已知因素.
- 孕前母亲压力对胎儿生长限制的直接影响,特别是对于妊娠年龄 (SGA) 来说很小,仍在调查中.
研究的目的:
- 调查孕前母亲压力与后代SGA风险之间的关联.
- 确定特定类型的孕产妇压力和社会经济因素,有助于SGA风险.
主要方法:
- 基于人口的回顾性队列分析,使用来自中国国家预孕保健项目 (NPHCP) (2010-2012) 的数据.
- 涉及572,989个个人.
- 使用后勤回归,合成少数群体过量采样技术 (SMOTE) 和倾向分数 (PS) 来分析孕前母亲压力与SGA之间的关联.
主要成果:
- 怀孕前母亲的压力与SGA风险增加有显著的关联 (OR 1.35,95% CI 1.20至1.51).
- 生活和经济压力因素在各种社会经济条件下显著增加了SGA风险.
- 具有较低社会经济地位 (教育程度较低,农民职业,农村居住,年龄较小) 的个人更容易受到压力和增加SGA风险.
结论:
- 怀孕前母亲的压力与SGA的风险增加有关.
- 较低的社会经济地位加剧了生活和经济压力因素的影响,导致SGA的发病率更高.
相关概念视频
Introduction to Stress and Lifestyle
42
Stress is a multifaceted response to events perceived as challenging or threatening, highlighting physical, emotional, cognitive, and behavioral reactions. Physically, stress can lead to fatigue, sleep disruptions, and various health issues such as frequent colds, chest pains, and nausea. Emotionally, it can manifest as anxiety, depression, irritability, and anger triggered by both minor and major life events. Cognitively, it may result in difficulty in concentration, memory, and...
42
Stress and Mental Health
42
Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...
Individuals with depression often experience challenges in both their personal and professional...
42
Psychoneuroimmunology: Diabetes and Cancer
14
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
14
Psychoneuroimmunology: Cardiovascular Disease
14
Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
A key area of focus in PNI is the relationship between stress and coronary...
14
Stress Prevention and Stress Management Techniques IV
12
Stress often leads to unhealthy habits like smoking, excessive drinking, and overeating, which offer short-term relief but ultimately increase long-term health risks. These behaviors create a cycle that temporarily lowers stress levels but can result in severe long-term health consequences. Breaking these habits is essential to reduce the risk of chronic diseases and improve overall well-being. Three primary changes that support better health include quitting smoking, reducing alcohol intake,...
12
Psychological Responses to Stress
14
Psychological responses to stress encompass the various cognitive and emotional reactions individuals experience when faced with challenging or threatening situations, such as a job loss. Prolonged exposure to stressors can disturb emotional balance, increasing negative emotions (e.g., anxiety and sadness) and diminishing positive emotions (e.g., joy and satisfaction). These persistent emotional shifts are associated with an increased risk of both physical illness and mental health issues, such...
14


