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中心静脉动脉二氧化碳部分压力差在术后认知功能障碍中的应用价值在急性大动脉剖析患者中

Lei Wang¹, Zhen Hong Wang², Duan Qi Zhu²

¹Department of Thoracic and Cardiovascular Surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.

Journal of cardiothoracic surgery

|January 5, 2025

概括

中心静脉动脉二氧化碳偏压差 (Pv-aCO2) 可以预测急性大动脉剖析患者的术后认知功能障碍 (POCD). 在手术期间监测Pv-aCO2有助于识别患有POCD风险的患者.

科学领域:

心血管外科心血管外科
神经科学是一个神经科学.
关键护理医学关键护理医学

背景情况:

手术后认知功能障碍 (POCD) 在接受急性大动脉解剖修复的患者中是一个重大问题.
准确的手术内监测对于预测和预防POCD至关重要.

研究的目的:

评估中央静脉动脉二氧化碳偏压差 (Pv-aCO2) 作为急性大动脉剖析患者POCD指标的临床实用性.
在这个患者群体中识别与POCD相关的风险因素.

主要方法:

对236名急性大动脉剖析患者进行了回顾性分析.
在手术期间采集血液气体样本以计算Pv-aCO2在各种手术阶段.
患者被分为高 (Pv-aCO2>6 mmHg) 和低 (Pv-aCO2 <6 mmHg) 的Pv-aCO2组.

主要成果:

高Pv-aCO2组表现出较高的POCD发病率和较低的迷你精神状态考试 (MMSE) 成绩.
在高Pv-aCO2组中观察到血清S100β水平升高.
晚年,女性性别,CPB时间和并发症被确定为POCD的独立风险因素.

结论:

在急性大动脉剖析中,Pv-aCO2有效地反映了手术期间的大脑代谢状态.
Pv-aCO2 作为POCD的宝贵的手术内预警指标.
建议对Pv-aCO2监测进行临床实施,以改善患者的治疗结果.

关键词:

急性大动脉剖析是什么中心静脉-动脉二氧化碳部分压力差认知功能障碍认知功能障碍这是一个MMSE.在S100ββ中,它是S100ββ.

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