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Updated: Jun 3, 2025

Protein Misfolding Cyclic Amplification of Prions
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Protein Misfolding Cyclic Amplification of Prions

Published on: November 7, 2012

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自组装蛋白聚合物的NIR光触发结构调制.

Jinhyeong Jang1,2, Yonghan Jo1, Chan Beum Park1

  • 1Department of Materials Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), 335 Science Road, Daejeon, 34141, Republic of Korea.

Small (Weinheim an der Bergstrasse, Germany)
|January 6, 2025
PubMed
概括

活性碳 (ACC) 纳米片,当暴露在近红外光下,可以分解错误折叠的蛋白 (PrP) 聚合物. 这种新的光动力学方法显示出治疗子疾病和保护大脑细胞的前景.

关键词:
活性炭活性炭的使用方法接近红外光的近红外光.子蛋白质是一种子蛋白质.自动组装的自动组装机

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相关概念视频

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Amyloid Fibrils

Amyloid fibrils are aggregates of misfolded proteins.  Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils. 
Amyloid deposits were observed as early as 1639 in the liver and the spleen.   In 1854, Rudolph Virchow performed iodine staining,...
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