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通过精确控制的酶去聚合及其对高油负载乳化功能的两功能化来制备细胞寡糖

Ziqian Li^1,2, Yan Zhang², Thomas Balle³

¹College of Food Science and Engineering, Collaborative Innovation Center for Modern Grain Circulation and Safety, Nanjing University of Finance and Economics, Nanjing 210023, China.

Journal of agricultural and food chemistry

|January 6, 2025

概括

细胞寡糖 (COS) 被制造和修改以产生两性COS (SAC12). SAC12有效地稳定了高油负荷的乳液,为营养药和制药应用提供了可持续的解决方案.

科学领域:

生物技术和生物材料
食品科学与技术食品科学与技术
化学工程是化学工程的重要组成部分.

背景情况:

细胞寡糖 (COS) 具有有益于肠道健康的益生菌性质.
从生物质中开发新的功能成分对于可持续应用至关重要.

研究的目的:

通过酶性水解产生具有特定链长的细胞寡糖 (COS).
为增强乳化性质而合成和表征两性COS (SAC12).
评估SAC12稳定乳液的稳定性和特性.

主要方法:

使用Ultimase BWL 40和Celluclast 1.5 L的纤维素的酶性水解产生COS.
在COS的基糖化过程中产生两性SAC12.
使用FTIR和1HNMR光谱学进行了表征.
乳液制备和稳定性评估 (滴滴大小,PDI,泽塔潜力).

主要成果:

酶性水解产生的COS主要由4-10个葡萄糖单位组成.
通过光谱方法证实了两性SAC12的成功合成.
SAC12稳定了70%重量%的鱼油在水中的乳液,具有纳米/微滴 (500-540nm) 和狭窄的PDI (<0.1).
乳液表现出高稳定性,具有强烈负的泽塔电位 (-45 到 -48 mV).

结论:

基糖化COS (SAC12) 显示出强大的没有表面活性剂的乳化能力.
SAC12为营养药和制药行业提供了一种可持续和多功能成分.
该研究强调了改性COS在先进材料应用中的潜力.

关键词:

细胞寡糖化物 (COS) 细胞寡糖化物细胞体内细胞体内.纤维素纤维素的使用方法缩乳液是缩的乳液.乳化剂乳化剂是一种乳化剂.可持续的解决方案可持续的解决方案

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