较高的体力活动水平与年轻成年人便微生物群的多样性和组成有关
Lourdes Ortiz-Alvarez1,2, Huiwen Xu1,2, Samuel Ruiz-Campos3,4
1PROFITH (PROmoting FITness and Health through Physical Activity) Research Group, Sport and Health University Research Institute (iMUDS), Department of Physical and Sports Education, Faculty of Sport Sciences, University of Granada, Granada, Spain.
Biology of sport
|January 6, 2025
概括
身体活动 (PA) 对年轻人的肠道微生物群多样性产生积极影响. 增强的活力PA与肠道细菌组成的特定变化有关,包括较少的Gammaproteobacteria.
科学领域:
- 微生物组研究的研究.
- 运动科学运动科学
- 人类生理学 人类生理学
背景情况:
- 身体活动 (PA) 对心脏代谢健康至关重要.
- 肠道微生物群的组成是代谢性疾病的潜在治疗点.
- 人类的PA和肠道微生物群之间的关系需要进一步研究.
研究的目的:
- 检查客观测量的PA与年轻成年人肠道微生物群多样性和组成之间的关联.
- 为了确定不同强度的PA是否会影响特定的微生物种群.
主要方法:
- 在88名年轻成年人 (平均年龄22.0岁) 的横截面研究中.
- 使用加速度计在7天内进行目标PA测量.
- 通过16S rRNA基因测序 (V3-V4区域) 来分析便微生物群.
主要成果:
- 总体PA和强大的PA与α多样性指数 (rho ≥0.23,P ≤0.034) 呈正相关性.
- 低活力的PA与更高的Gammaproteobacteria丰度相关 (q = 0.021).
- 低活力的PA与较低的Porphyromonadaceae (q = 0.031) 和Alistipes (q = 0.015) 丰度有关.
结论:
- 身体活动,特别是强烈的强度,与年轻成年人肠道微生物群的多样性有关.
- 强烈的PA影响特定细菌种的相对丰富性,包括Gammaproteobacteria,Porphyromonadaceae和Alistipes.
- 研究结果表明,PA是肠道微生物组成的调节器,具有潜在的健康影响.
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