在老年人中,身体活动,久坐和中风的关联
Long Bai1, Zongliang Wen1,2,3, Xuebing Yan3
1School of Public Health, Xuzhou Medical University, Xuzhou, China.
Frontiers in public health
|January 6, 2025
概括
久坐不动的行为会增加老年人中风的风险,而体力活动会减少中风的风险. 在这种关联中,C-反应蛋白起着作用,强调了积极的生活方式对老年人中风预防的重要性.
科学领域:
- 老年学是一门学科.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 脑卒中是老年人残疾和死亡的主要原因.
- 了解可修改的风险因素,如体力活动和久坐行为,对于预防中风至关重要.
- 以前的研究表明了潜在的联系,但老年人群中的特定关系需要进一步调查.
研究的目的:
- 为了研究身体活动,久坐不动行为和60岁及以上个体中风发病率之间的关系.
- 探索C-反应蛋白在静坐行为和中风之间的关联中的调解作用.
主要方法:
- 来自国家健康和营养检查调查 (NHANES) 的60岁以上的3010名参与者的数据分析.
- 通过关于久坐行为,体力活动和中风史的问卷收集数据.
- 使用加权多变量逻辑回归和平滑曲线拟合来评估非线性关系的统计分析.
主要成果:
- 在静坐行为和中风之间发现了显著的积极关联 (OR:2.602,p=0.003).
- 身体活动与中风有显著的负相关性 (OR:0.622,p=0.009).
- C-反应性蛋白调解了3.64%的静坐行为和中风之间的关联.
结论:
- 久坐不动的行为是老年人中风的重要危险因素.
- 增加体力活动与此年龄组中风风险降低有关.
- C-反应蛋白部分调解了久坐和中风之间的联系,这表明炎症途径.
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