在 inguinal 淋巴切除术后下肢的发生率:系统性审查和元分析
Brett A Hahn1, Milan C Richir2, Arjen J Witkamp2
1Department of Plastic and Reconstructive Surgery University Medical Center Utrecht Utrecht The Netherlands.
JPRAS open
|January 6, 2025
概括
下肢淋巴 (LEL) 影响24%的患者在 inguinal 淋巴结解剖后. 患病率因癌症类型而异,影响患者咨询和对LEL的治疗选择.
科学领域:
- 在瘤学瘤学.
- 手术瘤学手术瘤学
- 淋巴 edem 研究 研究 淋巴 edem 研究
背景情况:
- 针对各种癌症的内腔淋巴结剖析可以导致下肢淋巴 (LEL).
- 准确的LEL流行数据对于患者咨询和微手术干预的选择至关重要.
- 这一系统性审查和元分析综合了关于LEL患病率后腔淋巴切除术的现有文献.
研究的目的:
- 为在接受 inguinal 淋巴切除术的患者中报告的LEL 患病率提供全面的概述.
- 为了确定与LEL发展相关的患者特征.
- 为临床决策提供有关LEL预防和治疗的信息.
主要方法:
- 对23项研究进行了系统审查和元分析.
- 在Embase,PubMed和Web of Science数据库中进行的搜索.
- 使用"非随机化暴露研究中的偏差风险"工具评估偏差风险.
主要成果:
- 估计LEL的综合患病率为24% (95% CI: 17-31),具有很高的异质性 (I2=96%).
- 亚组分析显示,根据淋巴切除术的指示,LEL患病率存在显著差异.
- 具体的综合流行:黑色素瘤 (25.75%),阴茎癌 (12.22%),癌 (30.96%) 和各种 (13.62%).
结论:
- 恶性病变的病因是评估淋巴切除术后LEL风险的关键因素.
- 这些发现可以改善医生与患者之间关于LEL风险的沟通.
- 获得的知识有助于优化为LEL微手术干预患者的选择.
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