针对FAP导向的癌症治疗术的现状:一个文献计量分析
Dan Ruan1,2, Simin Wu1, Xuehua Lin1
1Department of Nuclear Medicine and Minnan PET Center, Xiamen Key Laboratory of Development and Translation of Radiopharmaceuticals, the First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen 361102, Fujian, China.
本文献分析对纤维细胞激活蛋白 (FAP) 和其用于癌症成像的放射性追踪剂的全球研究进行了映射. 它强调了FAP抑制剂 (FAPI) PET成像中的关键趋势,有影响力的出版物和未来研究方向.
科学领域:
- 在瘤学瘤学.
- 放射化学 放射化学是指辐射化学.
- 图书统计学 图书统计学
背景情况:
- 纤维细胞激活蛋白 (FAP) 在瘤学中对于瘤诊断和治疗至关重要.
- 基于昆的FAP抑制剂 (FAPI) 是癌症中正子发射断层扫描 (PET) 成像的有前途的放射追踪剂.
- 图书统计分析为科学领域的研究趋势和生产力提供了洞察力.
研究的目的:
- 对FAP和基于FAPI的放射追踪器的科学出版物进行文献计量分析.
- 量化和可视化研究趋势,协作和FAP研究中具有影响力的元素.
- 确定FAPI PET成像中的当前热点和未来研究方向.
主要方法:
- 使用R和VOSviewer进行图书统计分析. Web of Science核心数据收集.
- 根据国家,研究所,作者,期刊和关键词对出版物的量化和可视化.
- 检查FAPI放射性追踪器研究,包括方法,放射性核素,成像仪器和相关疾病.
主要成果:
- 从1992年到现在,已经确定了2664份与FAP相关的出版物.
- 德国,美国和中国在出版和合作方面处于领先地位;西南医学大学是最具生产力的研究所.
- 关键词包括FAP,Ga-FAPI和PET/CT;有影响力的期刊是欧洲核医学杂志和分子成像和核医学杂志.
结论:
- 图书统计数据显示,在FAP和FAPI放射性追踪器的开发中,全球有大量的研究活动和合作.
- 该分析强调了该领域的关键参与者,有影响力的出版物和占主导地位的研究主题.
- 这项研究提供了一个全面的概述,以指导FAP向癌症成像的未来研究工作.
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