基于多孔的支架的概述:发展,特性和生物医学应用
Amir Motaharinia1, Jaroslaw W Drelich2, Safian Sharif3
1Advanced Materials Research Center, Department of Materials Engineering, Najafabad Branch, Islamic Azad University, Najafabad, Iran.
Materials futures
|January 6, 2025
概括
本综述探讨了多孔 (Mg) 和其合金的制造方法,突出了它们在骨科植入物中的潜力. 需要进行进一步的研究,以优化骨组织工程的耐腐蚀性和骨质导电性等特性.
科学领域:
- 生物材料科学 生物材料科学
- 材料工程 材料工程 材料工程
- 整形外科手术 整形外科手术
背景情况:
- (Mg) 和其合金具有很高的生物相容性和生物降解性,使其成为骨科植入物和组织工程支架的前景.
- 在基于Mg的结构中制造均或梯度孔隙存在挑战,用于生物医学应用.
研究的目的:
- 对金属支架的制造工艺进行全面审查,重点关注基于Mg的合金.
- 分析基于Mg的支架在微观结构,机械性能,降解和生物性能方面的最新发现.
主要方法:
- 探索传统的制造技术 (例如,定向固化,图案造,空间持有器).
- 包括用于脚手架制造的现代增材制造方法.
- 对基于Mg的支架的体内和体外研究的审查.
主要成果:
- 基于Mg的支架由于有利的特性,显示了骨科应用的潜力.
- 基支架的微观结构,机械性能,降解和生物相容性已被广泛研究.
- 目前的研究表明需要增强耐腐蚀性和抗菌性质.
结论:
- 基于Mg的支架对骨组织工程具有前景,但需要进一步优化.
- 未来的研究应该专注于改善耐腐蚀性,抗菌活性,骨质导电性和骨质导电性.
- 为特定的细胞反应量身定制Mg支架对于临床转化至关重要.
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