医院抗菌药物管理的资金和资源对广泛抗生素使用的影响:一项横截面研究
Megan Tu1, Zong Heng Shi2, Valerie Leung3
1McMaster University, Hamilton, ON, Canada.
有专门资金的抗菌管理计划 (ASP) 可以减少特定的广泛抗生素使用,但不能减少整体使用. 提高ASP资源是限制针对性抗生素使用和打击抗菌素耐药性 (AMR) 的关键.
科学领域:
- 传染性疾病 传染性疾病
- 医院管理局 医院管理局
- 公共卫生 公共卫生
背景情况:
- 抗菌素耐药性 (AMR) 是一个日益增长的威胁,需要优化抗生素的使用.
- 抗菌药物管理计划 (ASP) 旨在减少不必要的广谱抗生素治疗.
- ASP资助对抗生素使用的影响需要进一步研究.
研究的目的:
- 评估抗菌药物管理计划 (ASP) 资金和资源与安大略省医院使用广谱抗生素之间的关联.
- 确定受ASP资源供应影响的特定抗生素类别.
主要方法:
- 一项横截面研究分析了2020年4月至2023年3月在安大略省63家医院的抗菌药物使用情况.
- 关于ASP资源和抗生素使用的数据是通过安大略省ASP景观调查收集的.
- 使用后勤回归来评估ASP资金与广泛抗生素使用之间的关系.
主要成果:
- 在63家医院中,48家医院报告了指定ASP资金/资源.
- 总体而言,广泛的抗生素使用与ASP资金没有显著的关联 (OR 0.97,P=0.79).
- ASP资金与减少使用诺基诺 (OR 0.67,P=0.03),克林达米辛 (OR 0.69,P=0.05) 和抗伪药剂 (OR 0.76,P=0.03) 的情况有关.
结论:
- 医院ASP的指定资金与某些宽谱抗生素的使用减少有关.
- 总体而言,ASP资金没有影响广谱抗生素的使用.
- 增加ASP资源可能对有针对性的抗生素减少和缓解AMR至关重要.
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