蜂在老年人群中没有显著调节免疫功能:初步研究
Lingling Pu1, Yonghui Wang1, Wei Pang1
1Tianjin Institute of Environmental and Operational Medicine, Tianjin, 300050, China.
Heliyon
|January 6, 2025
概括
这项研究发现,中国在老年人中暂时增强了免疫球蛋白G (IgG),但随着时间的推移,免疫功能恢复到正常水平. 蜂没有显著改变其他免疫标记物.
科学领域:
- 免疫学 免疫学 免疫学
- 老年学是一门学科.
- 自然产品研究 自然产品研究
背景情况:
- 老年人群因与年龄相关的免疫力下降而面临感染的易感性增加.
- 蜂是一种天然树脂混合物,由蜜蜂生产,以其潜在的免疫调节特性而闻名.
- 了解石等天然化合物对衰老免疫系统的影响,对于促进老年人健康至关重要.
研究的目的:
- 研究中华粉补充剂对老年人免疫功能的影响.
- 评估血清抗体,细胞因子和细胞免疫反应的变化.
主要方法:
- 一项为期12周的随机对照试验,涉及62名社区居住的老年人 (60-80岁) 在中国天津.
- 参与者每天接受600毫克的中国或安慰剂.
- 测量了包括血清抗体 (如IgG),细胞因子,淋巴细胞增殖 (MTT测定) 和中性粒细胞功能 (葡萄球菌方法) 在内的免疫标志物.
主要成果:
- 在 прополис组的第6周观察到免疫球蛋白G (IgG) 水平的暂时上升,到第12周恢复到基线.
- 在整个研究中,在和对照组之间,在其他测量的血清抗体,细胞因子,淋巴细胞或中性粒细胞功能中没有发现显著差异.
- 用24小时回忆方法评估饮食摄入量.
结论:
- 中国树在老年人中显示出对IgG分泌的短期刺激作用.
- 观察到的的免疫效应是暂时的,在12周的研究期间,水平恢复到基线.
- прополис补充剂在这个老年人群中评估的免疫标志物中没有产生显著的长期或广泛的改善.
更多相关视频
12:21A Mouse Model for the Transition of Streptococcus pneumoniae from Colonizer to Pathogen upon Viral Co-Infection Recapitulates Age-Exacerbated Illness
Published on: September 28, 2022
2.3K
10:58Obtaining Specimens with Slowed, Accelerated and Reversed Aging in the Honey Bee Model
Published on: August 29, 2013
11.2K
相关概念视频
01:26Factors Affecting the Risk of Infection
10.5K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
10.5K
01:26Aging
19
Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
19