克隆尼丁对高体积,低度尾尾外皮带治疗的持续时间的影响
Christopher Heine1, Michelle Rovner1, William Irick1
1Anesthesiology and Perioperative Medicine, Medical University of South Carolina, Charleston, USA.
Cureus
|January 6, 2025
概括
将克洛尼丁添加到尾巴块中并没有扩大疼痛缓解或减少接受割礼的幼儿出现动荡. 这项研究表明,当使用高容量,低度罗皮瓦卡因时,克洛尼丁在这个儿科外科患者群体中没有额外的益处.
科学领域:
- 儿科麻醉学 儿科麻醉学
- 区域麻醉 区域麻醉
- 疼痛管理 疼痛管理
背景情况:
- 尾巴块是一种标准的儿科区域麻醉,用于治疗割礼疼痛.
- 克洛尼丁和高容量,低度 (HVLC) 技术可以延长尾巴块的持续时间.
- 出现动荡 (EA) 是儿科麻醉的一个问题.
研究的目的:
- 在接受割礼的儿科患者中,使用HVLC局部麻醉剂与克洛尼丁 (clonidine) 和没有克洛尼丁 (clonidine) 进行尾巴阻塞的持续时间比较.
- 作为次要结局,评估外周克洛尼丁对术后出现动荡 (EA) 的影响.
主要方法:
- 一项前性,随机的,观察者盲目的研究,涉及129名接受割礼的儿童 (0-3岁).
- 参与者接受了罗皮瓦卡因 (HVLC) 尾部注射,有或没有克隆尼丁.
- 通过对乙氨基的使用来评估疼痛,并使用小儿麻醉突发 Delirium (PAED) 尺度来评估EA.
主要成果:
- 在群体之间的人口统计,麻醉,手术或出院时间方面没有发现显著差异.
- 第一次术后乙氨基剂的中位时间为335分钟 (不含克隆尼丁) 与381分钟 (克隆尼丁),P=0.901.1.
- 平均PAED得分为6.5 (没有克隆尼丁) 和6.4 (克隆尼丁),P=0.894.
结论:
- 在接受割礼的儿童中,添加克洛尼丁到HVLC尾部注射的罗皮瓦卡因并没有延长到第一个乙氨基剂量的时间.
- 克隆丁在这个患者群体中没有显著影响术后出现动荡的发生.
- 在儿童割礼中,添加克隆尼丁到HVLC尾部麻醉中,没有明显的好处.
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