针对认知衰退的多组分干预措施的成本效益
Christian Brettschneider1, Elżbieta Buczak-Stec1, Melanie Luppa2
1Department of Health Economics and Health Services Research, Hamburg Center for Health Economics University Medical Center Hamburg-Eppendorf Hamburg Germany.
Alzheimer's & dementia (New York, N. Y.)
|January 6, 2025
概括
一种多领域的生活方式干预措施,以预防高危老年人的认知衰退是具有成本效益的. 这项干预表明了有利的增量成本效益比率,这表明医疗保健对认知健康的投资有价值.
科学领域:
- 老年学是一门学科.
- 公共卫生 公共卫生
- 卫生经济学 卫生经济学
背景情况:
- 痴呆症和认知衰退的社会成本是相当大的,并且正在上升.
- 老年人口正在增加,加剧了认知障碍的负担.
- 预防策略对于减轻未来的医疗需求至关重要.
研究的目的:
- 评估多领域干预措施的成本效益,以预防高风险老年人的认知衰退.
- 将多领域的生活方式干预与一般健康建议进行比较.
- 评估一种新的痴呆症预防方法的经济价值.
主要方法:
- 一个多中心,集群随机对照试验 (AgeWell.de) 涉及819名参与者 (60-77岁) 患痴呆风险增加.
- 从社会角度对两年时间的成本效益分析.
- 使用EQ-5D-5L.测量医疗保健利用率和经质量调整的寿命年 (QALYs).
主要成果:
- 与对照组相比,干预组的成本较高 (+445.88欧元),但获得了额外的QALY (+0.026).
- 增量成本效益比率 (ICER) 每个QALY为17,149.23欧元.
- 在5万欧元/QALY的支付意愿下,成本效益的概率达到了59%,在女性中取得了有希望的结果.
结论:
- 与一般健康咨询相比,多领域干预是具有成本效益的,考虑到支付意愿和研究的时间范围.
- 这项干预措施显示出降低认知衰退的社会负担的潜力.
- 需要对更长的时间进行进一步的研究,以充分确定长期益处.
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