患有非综合性口腔裂患者的牙异常:系统性审查和元分析
Sara Garcia Azevedo1, Lilianny Querino Rocha de Oliveira2, Hercílio Martelli-Júnior3,4
1Department of Oral Diagnosis, School of Dentistry, University of Campinas, Piracicaba, São Paulo, Brazil.
Oral diseases
|January 6, 2025
概括
患有非综合症口腔口腔裂 (NSOC) 的患者在永久牙中显示出更高频率的牙异常 (TA),根据裂区域内或外的位置而有所不同. 牙科管理应根据特定的裂亚型和TA呈现量身定制.
科学领域:
- 牙异常 牙异常
- 头骨面部的发展
- 公共卫生 公共卫生
背景情况:
- 非综合性口腔裂 (NSOC) 是一种常见的先天性疾病.
- 牙异常 (TA) 经常在患有NSOC的个体中观察到.
- 了解TA模式对于有效的牙科管理至关重要.
研究的目的:
- 评估非综合性口腔口腔裂 (NSOC) 患者的叶落和永久牙异常 (TA) 的频率.
- 为了比较裂口区域内外的TA发生情况.
- 分析不同NSOC亚型和种群的TA变化.
主要方法:
- 在多个数据库 (Cochrane,PubMed,Scopus等) 进行系统的文献搜索. ) 的情况.
- 75项纳入研究 (27,703名患者) 的元分析.
- 使用Joanna Briggs研究所和GRADE方法评估的偏见风险和证据确定性.
主要成果:
- 在永久牙中,裂口区域以外的牙生殖和巨牙的几率更高.
- 在永久牙中,裂口区域内增加牙生殖,微牙,巨牙,超数牙以及牙质低成形的风险.
- 微牙是唯一一个在裂口区域之外的叶落式牙中明显更频繁的TA.
结论:
- 在NSOC患者的永久牙中,TA更频繁,具有特定位置的差异.
- 在全球不同的人口中,TA的患病率有很大差异.
- 针对性牙科管理和早期干预对于NSOC患者至关重要.
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