儿童和青少年的睡眠相关呼吸障碍和下尿道功能障碍:一个范围审查
Maayke van Galen1,2, Bibi Huskens1,2, Benodet Tak2
1Behavioral Science Institute, Radboud University, Nijmegen, The Netherlands.
Neurourology and urodynamics
|January 6, 2025
概括
睡眠呼吸障碍 (SDB) 显然与儿童的夜间尿液 (NE) 有关. 腺切除术可以有效地治疗SDB患者的NE,但对于其他尿道问题和发育迟缓需要更多的研究.
科学领域:
- 儿科睡眠医学 儿科睡眠医学
- 儿科泌尿外科 儿科泌尿外科
- 发育儿科 发育儿科
背景情况:
- 睡眠呼吸障碍 (SDB),下泌尿道功能障碍 (LUTD) 和夜间尿液 (NE) 在儿童和青少年中很普遍,影响社会和情绪发展.
- 虽然已知成人SDB-NE关联,但儿科研究是有限的,需要对当前知识进行审查.
研究的目的:
- 进行范围审查,绘制SDB和LUTD在儿童和青少年之间的关联现有知识的地图.
- 识别有关SDB,LUTD和儿科群体相关并发症的文献上的差距.
主要方法:
- 在四个电子数据库 (Embase,PsychInfo,Pubmed,Web of Science) 进行了全面的搜索.
- 纳入标准集中在涉及儿童/青少年 (5-18岁) 患有SDB和LUTD表现的研究上,这些研究以英语或荷兰语出版.
- 方法质量使用量化研究质量评估工具 (QATQS) 进行了评估.
主要成果:
- 包括17篇文章,证实了SDB和儿童NE之间的明显关联.
- 关于SDB对其他下泌尿道症状 (LUTS) 和发育迟缓 (DDs) 的影响的信息有限.
- 腺切除术 (T&A) 在患有SDB的儿童中对NE产生了显著的积极影响.
结论:
- 由于对唤醒和夜间尿液产生影响,SDB/阻塞性睡眠呼吸暂停 (OSA) 和NE之间存在强烈联系.
- 在SDB患者中,T&A是一种潜在的NE治疗方法,这些患者对标准疗法没有反应.
- 进一步的研究至关重要,以了解机制,探索与其他LUTS/DDs的关联,并指导多学科治疗并发性疾病的治疗.
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