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Updated: Jun 3, 2025

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细胞类型特定的表观遗传钟,以量化细胞类型分辨率的生物年龄

Huige Tong1, Xiaolong Guo1, Macsue Jacques2

  • 1CAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute of Nutrition and Health, Shanghai Institute for Biological Sciences, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai 200031, China.

Aging
|January 6, 2025
PubMed
概括

这项研究开发了细胞类型特定的表观遗传钟,以准确测量生物年龄. 这些专门的钟表揭示了阿尔茨海默病和肝脏疾病的年龄加速,表现优于一般的钟表.

关键词:
阿尔茨海默氏症是阿尔茨海默氏症的一种疾病.通过DNA甲基化.生物衰老 生物衰老细胞类型的解解.遗传表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表观表肥胖 肥胖 肥胖 肥胖 肥胖 肥胖 肥胖 肥胖

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