相关实验视频

Updated: Jun 3, 2025

Methodology for Accurate Detection of Mitochondrial DNA Methylation
12:11

Methodology for Accurate Detection of Mitochondrial DNA Methylation

Published on: May 20, 2018

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肝细胞中烧伤诱导的线粒体功能障碍:受甲基化控制的J蛋白沉默的作用

Akshay Pratap1, Kenneth Meza Monge, Andrea C Qualman

  • 1From the Division of Gastrointestinal, Trauma, and Endocrine Surgery, Department of Surgery (A.P., K.M.M., A.C.Q., E.J.K., J.-P.I.), Division of Burn Research (E.J.K.), and Division of Alcohol Research (E.J.K.), Department of Immunology and Microbiology, University of Colorado, Aurora, Colorado.

The journal of trauma and acute care surgery
|January 6, 2025
PubMed
概括

甲基化控制的J蛋白 (MCJ) 通过增加氧化应激和线粒体功能障碍,加剧烧伤后的肝损伤. 沉默MCJ保护肝细胞,这表明它可以.

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Experimental Protocol for Detecting Mitochondrial Function in Hepatocytes Exposed to Organochlorine Pesticides08:39

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Isolation of Primary Mouse Hepatocytes for Nascent Protein Synthesis Analysis by Non-radioactive L-azidohomoalanine Labeling Method08:04

Isolation of Primary Mouse Hepatocytes for Nascent Protein Synthesis Analysis by Non-radioactive L-azidohomoalanine Labeling Method

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相关概念视频

Epigenetic Regulation01:37

Epigenetic Regulation

Epigenetic changes alter the physical structure of the DNA without changing the genetic sequence and often regulate whether genes are turned on or off. This regulation ensures that each cell produces only proteins necessary for its function. For example, proteins that promote bone growth are not produced in muscle cells. Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
X-chromosome...
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Covalently Linked Protein Regulators02:04

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Electron Transport Chain: Complex I and II

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