多药性和抗胆固醇负担作为手术后痴呆症的风险因素在外科医学中
Henriette Louise Moellmann1, Soufian Boulghoudan2, Julian Kuhlmann2
1Cranio-and-Maxillo Facial Surgery, University Hospital Düsseldorf, Moorenstraße 5, 40225, Düsseldorf, Germany. henriettelouise.moellmann@med.uni-duesseldorf.de.
Zeitschrift fur Gerontologie und Geriatrie
|January 6, 2025
概括
服用某些药物的老年患者面临更高的妄想风险. 抗胆固醇负担 (ACB) 评分是一种简单的工具,用于识别有风险的个体,有助于进行手术前老年患者的评估.
科学领域:
- 老年医学 老年医学
- 药理学 药理学是指药理学的学科.
- 麻醉学 麻醉学
背景情况:
- 多药性在老年患者中很普遍.
- 药物的抗胆固醇负担是术后妄想的重要危险因素.
- 胆固醇系统与年龄相关的变化加剧了这种风险.
研究的目的:
- 在老年患者中调查术前药物,抗胆固醇负担 (ACB) 和术后妄想之间的关联.
- 确定有助于增加妄想风险的特定药物.
主要方法:
- 这是一项前性研究,涉及421名患者.
- 术前药物审查和ACB计算.
- 每天进行术后妄想查.
主要成果:
- 抗抑郁药物,抗糖尿病药物,神经乱药物和帕金森病药物与明显更高的妄想风险有关.
- 显著的百分比的患者 (10.4%) 具有抗胆固醇负担.
- 患有ACB的患者患上妄想症的风险增加了2.79倍.
结论:
- 标准化药物记录对于识别患有 Delirium 风险的患者至关重要.
- 该ACB评分是一个简单的,可靠的选工具,用于抗胆固醇负担.
- 应将ACB评估整合到手术前老年医疗评估中.
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