的特征在预测上部内镜诊断的胃中恶性的表现
Ankur P Patel1, Cassandra Gandle2, Elliot Baerman1
1Department of Medicine, Baylor College of Medicine, Houston, TX.
Journal of clinical gastroenterology
|January 6, 2025
概括
内镜的特征,如不规则的边界和升高的边界可以预测胃的恶性瘤,可能减少不必要的监视内镜. 该模型有助于识别需要进一步监测的高风险患者.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 诊断内镜检查 诊断内镜检查
背景情况:
- 胃诊断后的监视内镜是常见的,但昂贵和危险.
- 内镜特征可能有助于识别恶性胃,指导需要监测.
研究的目的:
- 为了评估内镜特征对患有恶性瘤的预测价值.
- 为了识别具有恶性潜力的胃,以优化监测内镜决策.
主要方法:
- 从2019年2月至2021年7月,对338名胃患者进行了回顾性分析.
- 恶性病因由活检组织病理学确定;良性包括治愈的.
- 分析的内镜特征:森林的分类,位置,大小,升高的边缘,不规则的边缘和胃缩.
主要成果:
- 12%的胃 (41/338) 是恶性的.
- 不规则的边缘 (AUROC:0.89),胃缩 (AUROC:0.87),和升高的边缘 (AUROC:0.84) 是强有力的预测因素.
- 一个多变量模型 (位置,不规则/升高的边界,缩) 实现了高歧视 (AUROC:0.96) 与低假负值 (0.4%).
结论:
- 结合内镜特征和组织病理学的预测模型准确地识别恶性胃.
- 这种模型可以帮助选择最能从监视内镜中受益的患者,减少不必要的手术.
相关概念视频
Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies
62
Peptic ulcer disease (PUD) presents with diverse symptoms depending on the location and severity of the ulcer. Clinical manifestations of peptic ulcer include dull pain and a burning sensation in the mid-epigastric region.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
62
Peptic Ulcer Disease I: Introduction
81
Peptic Ulcer Disease (PUD) is characterized by mucosal excavation in the esophagus, stomach, pylorus, or duodenum. It can manifest as acute or chronic based on the extent and duration of mucosal involvement.
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
81
Pathophysiology of Peptic Ulcer Disease: Mucosal Defense Factors
305
Peptic ulcer disease, commonly called PUD, represents a multifaceted condition characterized by disruptions in the lining of the gastrointestinal (GI) tract. Central to the protection of the gastrointestinal lining is the mucosal-bicarbonate barrier. This physiological defense mechanism is a formidable shield against the corrosive effects of gastric acid and pepsin secretion in the stomach. Its role is pivotal in maintaining the structural integrity of the stomach's inner lining.
305
Peptic Ulcer Disease V: Surgical Management and Nursing Care
143
Surgical management and nursing care are crucial in treating Peptic Ulcer Disease (PUD). Here is an organized and enhanced overview of the surgical interventions and the associated nursing care for PUD:
Surgical Interventions for Peptic Ulcer Disease
Surgical Interventions for Peptic Ulcer Disease
143
Peptic Ulcer Disease IV: Management
44
Medical treatment strategies for peptic ulcers encompass various methods. The primary goal of treatment is to diminish gastric acidity and strengthen mucosal defense mechanisms.
The therapeutic approach involves ensuring adequate rest, implementing drug therapy, promoting smoking cessation, making dietary modifications, and emphasizing long-term follow-up care.
Pharmacological management
The prevailing therapy for peptic ulcers involves a combination of managing the patient's current...
The therapeutic approach involves ensuring adequate rest, implementing drug therapy, promoting smoking cessation, making dietary modifications, and emphasizing long-term follow-up care.
Pharmacological management
The prevailing therapy for peptic ulcers involves a combination of managing the patient's current...
44
Drugs for Peptic Ulcer Disease: Sucralfate as Mucosal Protective Agents
310
In the intricate landscape of the gastric lumen, excessive acid secretion disrupts the natural defense mechanisms, weakening the mucus-bicarbonate barrier. This vulnerability allows pepsin to infiltrate epithelial cells, digesting mucosal proteins and triggering erosion, leading to ulcer formation.
In this scenario, mucosal protective agents like sucralfate play an essential role. Sucralfate, a complex of sulfated sucrose and aluminum hydroxide, demonstrates its usefulness in acidic conditions,...
In this scenario, mucosal protective agents like sucralfate play an essential role. Sucralfate, a complex of sulfated sucrose and aluminum hydroxide, demonstrates its usefulness in acidic conditions,...
310


