肠-大脑轴和刺激性肠综合征在由于SARS-CoV-2流行病的锁定期间:基于调查的研究:基于调查的研究
María Marta Piskorz1, Juan Pablo Stefanolo2, Agustin Ibañez3,4,5,6
1Hospital de Clínicas José de San Martin. Buenos Aires University.
随着COVID-19的封锁,通过减少肠-大脑轴的压力因素,改善了腹性易怒肠综合征 (IBS-D) 患者的症状. 这导致IBS-D患者的症状强度,焦虑和体质化降低.
科学领域:
- 胃肠病学 胃肠病学
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
背景情况:
- 刺激性肠综合征 (IBS) 对社会情绪因素很敏感.
- 随着COVID-19的封锁,出现了一个独特的场景,社会互动发生了变化,可能会影响IBS.
- 了解IBS的肠-大脑轴对于控制症状至关重要.
研究的目的:
- 评估COVID-19封锁措施对IBS患者的影响.
- 评估关闭期间肠-大脑轴相关症状的变化.
- 专注于阿根廷布宜诺斯艾利斯的腹性IBS (IBS-D) 患者.
主要方法:
- 重新调查之前参与研究的IBS-D患者.
- 在封锁期间使用症状严重程度尺度.
- 评估心理因素,包括焦虑,抑郁和体化.
主要成果:
- 观察到严重的IBS症状显著减少 (40.4%与25%相比).
- 腹部不适,胀气和整体症状强度显著降低.
- 在封锁期间,焦虑和严重的身体化水平也下降了.
结论:
- COVID-19封锁与IBS-D患者的改善临床状态相关.
- 在肠-大脑轴上减少对外部压力因素的暴露可能有助于症状改善.
- 这些发现突出了环境因素和IBS症状之间的相互作用.
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