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对肺癌患者的横截面研究作为腹腔大动脉动脉瘤的潜在高风险因素

Hye Ran Gwon^1,2, A La Woo², Seung Hyun Yong²

¹Division of Pulmonology, National Cancer Center, Goyang, Gyeonggi, Korea.

|January 6, 2025

概括

腹腔大动脉瘤 (AAA) 在非小细胞肺癌 (NSCLC) 患者中明显更常见. 早期NSCLC患者,特别是老年吸烟者,应定期接受AAA监测,以改善生存率.

科学领域:

心血管外科心血管外科
胸部瘤学胸部瘤学
诊断成像诊断成像诊断成像

背景情况:

腹腔大动脉瘤 (AAA) 在非小细胞肺癌 (NSCLC) 患者中更为普遍.
破裂的AAA具有致命风险,因此及时的AAA管理对于NSCLC患者的长期存活至关重要.
本研究评估了可切除NSCLC患者的AAA患病率和特征,这些患者有资格接受监测.

研究的目的:

确定可切除NSCLC的患者中AAA的患病率.
在这个患者群体中确定与AAA相关的风险因素.
在早期NSCLC中为AAA提供监测策略的信息.

主要方法:

对1019名可切除的NSCLC患者的回顾性审查 (2019年1月 - 2020年11月).
2,899名无癌症个体的对照组进行CT扫描 (2018年1月 - 2019年12月).
多变量回归分析以确定AAA的独立风险因素.

主要成果:

在NSCLC患者中,AAA患病率为3.8%,对照组为0.2% (OR,19,19;P<0.001).
在NSCLC患者中,AAA的独立风险因素包括男性性别,年龄较大,目前的吸烟和冠状动脉疾病.
对于每个风险因素,报告了特定的几率比率和置信区间.

结论:

与无癌症患者相比,早期肺癌患者的AAA发病率明显高.
建议对早期NSCLC患者进行定期AAA监测,特别是60岁以上的吸烟者.
将AAA查整合到肺癌监测中可以提高患者的生存率.

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