对DENV的低预先存在的抗NS1幽默免疫与妊娠期ZIKV暴露后的小头发育有关

Sebastián Castro-Trujillo1, William R Mejía2,3, Katherine Segura1,4

  • 1División de Inmunología, Programa de Medicina, Facultad de Ciencias de la Salud, Universidad Surcolombiana, Neiva, Huila, Colombia.

PubMed
概括

针对登革热病毒 (DENV) 的母体抗体NS1可以保护婴儿免受与寨卡病毒 (ZIKV) 相关的小头症. 在母亲体内先前存在的DENV IgG-NS1抗体显示出与先天性寨卡综合征 (CZS) 的保护性关联.

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