患者因素影响医疗治疗慢性鼻炎中SNOT-22临床重要差异最小
Mohamed A Aboueisha1,2, Felix E Fernández-Penny1,3, Jacob Hodges1
1Department of Otolaryngology-Head and Neck Surgery, University of Washington, Seattle, Washington, USA.
International forum of allergy & rhinology
|January 6, 2025
概括
社会人口结构和并发症显著影响慢性鼻炎 (CRS) 患者的22项鼻结局测试 (SNOT-22) 的临床重要差异最小值 (MCID). 抑郁症和偏头痛等因素会影响人们对治疗结果的看法.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 健康 结果 研究 研究 结果
- 患者报告的结果
背景情况:
- 在慢性鼻炎 (CRS) 中评估有意义的治疗改善依赖于临床重要差异最小值 (MCID).
- 对22项鼻结局测试 (SNOT-22) 影响MCID的患者特异性因素仍然不完全理解.
研究的目的:
- 调查社会人口统计学和并发性疾病对医疗治疗的CRS患者SNOT-22分数的MCID的影响.
- 识别影响临床上有意义的改善感知的特定患者特征.
主要方法:
- 一组接受医疗治疗的221名CRS患者提供了SNOT-22分数和基于的变化评估.
- 收集了社会人口统计数据,病史,并发症和治疗前后SNOT-22分数.
- 调整后勤回归分析确定了与MCID相关的因素.
主要成果:
- 近一半 (43.9%) 的CRS患者在治疗后报告改善.
- 性别,教育,抑郁和偏头痛显著影响了人们对治疗结果的看法.
- 结合这些因素的预测模型显示出良好的区分能力 (AUC = 0.818).
结论:
- 患者的社会人口统计和并发症在CRS中对SNOT-22的MCID计算有很大影响.
- 了解这些个别因素对于解释患者报告的结果和治疗疗效至关重要.
- 这项研究突出了影响CRS患者感知临床改善的因素的复杂性.
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