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Identification of Virulence Markers of Mycobacterium abscessus for Intracellular Replication in Phagocytes
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两部分的MtrAB系统对于Mycobacterium abscessus的内在耐药性和毒性至关重要

Jingran Zhang1, Yanan Ju1, Lijie Li1

  • 1School of Basic Medical Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China; Institute of Drug Discovery, State Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health (GIBH), Chinese Academy of Sciences (CAS), Guangzhou, China; China-New Zealand Joint Laboratory on Biomedicine and Health, Guangzhou Institutes of Biomedicine and Health (GIBH), Chinese Academy of Sciences (CAS), Guangzhou, China.

International journal of antimicrobial agents
|January 6, 2025
PubMed
概括

在Mycobacterium abscessus (Mab) 中准MtrA和MtrB显著提高了抗生素敏感性,并降低了毒性. 这些蛋白质是Mab抗药性和感染严重性的关键,使它们成为有希望的治疗点.

关键词:
细胞分裂 细胞分裂内在电阻是内在的电阻.这种细菌是Mycobacterium abscessus.两个组成部分的系统MtrABAB.病毒性 病毒性

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