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通过ceRNA网络分析,对GLP-1受体激动剂诱导的体重减轻的机制性见解

Wenxin Li1, Xinyu Zhang2, Jiamin Song1

  • 1Department of Endocrinology and Metabolism, The Affiliated Hospital of Jiangsu University, Institute of Endocrine and Metabolic Diseases, Jiangsu University, Zhenjiang 212000, Jiangsu, China.

Genomics
|January 6, 2025
PubMed
概括

类似葡萄糖-1受体激动剂 (GLP-1RA) 可能通过激活PI3K-Akt和AMPK通路来促进体重减轻. 这涉及到竞争的内源RNA (ceRNA) 网络的循环RNA (circRNAs) 影响肥胖中的脂质代谢.

关键词:
AMPK信号通道的信号通道.竞争的内源性RNA网络.它是GLP-1受体激动剂.肥胖问题 肥胖问题通过PI3K-Akt信号通路传递信号.

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