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Updated: Jun 3, 2025

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在CD4+内巨细胞动脉炎的因果基因鉴定 记忆T细胞:多omics和表达的整合 定量特征局部分析

Qiyi Yu1, Yifan Wu2, Xianda Ma3

  • 1Carnegie Mellon University, Pittsburgh, USA. qiyiy@andrew.cmu.edu.

Inflammation research : official journal of the European Histamine Research Society ... [et al.]
|January 6, 2025
PubMed
概括

巨细胞动脉炎 (GCA) 的风险与CD4+记忆T细胞有关. DDIT4基因通过在这些细胞中引起慢性炎症来促进GCA,突出其在疾病发展中的作用.

关键词:
CD4+ 记忆T细胞 CD4+ 记忆T细胞大细胞动脉炎的巨细胞动脉炎门德尔的随机化多个omics的多个omics.单细胞机是一种单细胞机.

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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
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