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Updated: May 7, 2025

Real-time Imaging of Single Engineered RNA Transcripts in Living Cells Using Ratiometric Bimolecular Beacons
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Published on: August 6, 2014

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在活细胞中设计共价小分子-RNA复合体.

Raphael Bereiter1, Laurin Flemmich1, Kamila Nykiel2

  • 1University of Innsbruck, Institute of Organic Chemistry and Center for Molecular Biosciences (CMBI), Innsbruck, Austria.

Nature chemical biology
|January 6, 2025
PubMed
概括

研究人员开发了一种新的方法,用于在活细胞中对共价RNA进行标记,使用工程制造的aptamer-ligand复合体. 这种结构导向的方法能够精确地定位和监测RNA动态,在药物发现中具有潜在的应用.

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